Title: Etersalate
CAS Registry Number: 62992-61-4
CAS Name: 2-(Acetyloxy)benzoic acid 2-[4-(acetylamino)phenoxy]ethyl ester
Additional Names: 2-(4-acetamidophenoxy)ethyl 2-acetoxybenzoate; eterilate; etherylate; eterylate
Trademarks: Daital (Alter)
Molecular Formula: C19H19NO6
Molecular Weight: 357.36
Percent Composition: C 63.86%, H 5.36%, N 3.92%, O 26.86%
Literature References: Deriv of aspirin. Prepn: C. S. Letelier, F. C. Grafulia, DE 2538206; eidem, US 4014921 (both 1977 to Alter); C. S. Letelier et al., Arch. Farmacol. Toxicol. 4, 153 (1978). Effect on in vitro platelet function in human plasma: M. P. Ortega et al., ibid. 6, 31 (1980). In vivo effects on primary immune response: I. Barasoain et al., Immunopharmacology 2, 293 (1980). Comparative toxicity study and gastric tolerance: S. Alonso et al., Arch. Farmacol. Toxicol. 4, 349 (1978).
Properties: Cryst from methanol, mp 139-141°. LD10 orally in rats: 7000 mg/kg (Leterier, Grafulia, 1977).
Melting point: mp 139-141°
Toxicity data: LD10 orally in rats: 7000 mg/kg (Leterier, Grafulia, 1977)
Therap-Cat: Analgesic; anti-inflammatory; antipyretic.
Keywords: Analgesic (Non-Narcotic); Anti-inflammatory (Nonsteroidal); Salicylic Acid Derivatives; Antipyretic.
Status: This monograph has been retired and is no longer subject to revision or update. |