Title: Furtrethonium
CAS Registry Number: 7618-86-2
CAS Name: N,N,N-Trimethyl-2-furanmethanaminium
Additional Names: furfuryltrimethylammonium; trimethylfurfurylammonium; furtrimethonium
Trademarks: Furmethide (SK & F)
Molecular Formula: [C8H14NO]+
Literature References: Prepn of salts: Nabenhauer, US 2185220 (1938 to SK & F); Weilmuenster, Jordan, J. Am. Chem. Soc. 67, 415 (1945); Khromov-Borisov et al., J. Gen. Chem. USSR 24, 2021 (1954).
Derivative Type: Iodide
CAS Registry Number: 541-64-0
Trademarks: Furamon; Furanol
Molecular Formula: C8H14INO
Molecular Weight: 267.11
Percent Composition: C 35.97%, H 5.28%, I 47.51%, N 5.24%, O 5.99%
Properties: Crystals from ethanol + ethyl acetate, mp 116-117° (Weilmuenster, Jordan); also reported as mp 118-120° (Khromov-Borisov). Soluble in water, alcohol. Practically insol in benzene. pH of 1% aq soln, 5.3-6.0.
Melting point: mp 116-117° (Weilmuenster, Jordan); mp 118-120° (Khromov-Borisov)
Derivative Type: Benzenesulfonate
Trademarks: Benzamon
Molecular Formula: C14H19NO4S
Molecular Weight: 297.37
Percent Composition: C 56.55%, H 6.44%, N 4.71%, O 21.52%, S 10.78%
Properties: Crystals from ethanol + butyl acetate, mp 134-135° (Kromov-Borisov). Soluble in water, alcohol.
Melting point: mp 134-135° (Kromov-Borisov)
Derivative Type: p-Toluenesulfonate
Trademarks: Fisostina
Molecular Formula: C15H21NO4S
Molecular Weight: 311.40
Percent Composition: C 57.86%, H 6.80%, N 4.50%, O 20.55%, S 10.30%
Therap-Cat: Cholinergic. Iodide as parasympathomimetic.
Keywords: Cholinergic. |