Title: Laurolinium Acetate
CAS Registry Number: 146-37-2
CAS Name: 4-Amino-1-dodecyl-2-methylquinolinium acetate
Additional Names: 4-amino-1-dodecylquinaldinium acetate; 1-dodecyl-4-aminoquinaldinium acetate
Trademarks: Laurodin
Molecular Formula: C24H38N2O2
Molecular Weight: 386.57
Percent Composition: C 74.57%, H 9.91%, N 7.25%, O 8.28%
Literature References: Prepn: D. Caldwell et al., J. Pharm. Pharmacol. 13, 554 (1961); D. Caldwell, L. R. Rowe, US 2997476 (1961 to Allen & Hanburys). Toxicity data: W. A. Cox, P. F. D'Arcy, J. Pharm. Pharmacol. 15, 129 (1963).
Properties: Crystals from acetone, mp 170-171°. Freely sol in water. About 1 g dissolves in 2 ml of water at 20°. LD50 in mice (mg/kg): 131 ±36.2 orally; 30.2 ±5.6 s.c.; 6.0 ±04 i.v.; 2.3 ±0.2 i.p. (Cox, D'Arcy).
Melting point: mp 170-171°
Toxicity data: LD50 in mice (mg/kg): 131 ±36.2 orally; 30.2 ±5.6 s.c.; 6.0 ±04 i.v.; 2.3 ±0.2 i.p. (Cox, D'Arcy)
Therap-Cat: Antiseptic.
Keywords: Antiseptic/Disinfectant; Quaternary Ammonium Compounds. |