Title: o-Thymotic Acid
CAS Registry Number: 548-51-6
CAS Name: 2-Hydroxy-6-methyl-3-(1-methylethyl)benzoic acid
Additional Names: 3-hydroxy-2-p-cymenecarboxylic acid; o-thymotinic acid; 6-methyl-3-isopropylsalicylic acid
Molecular Formula: C11H14O3
Molecular Weight: 194.23
Percent Composition: C 68.02%, H 7.27%, O 24.71%
Literature References: Prepn from thymol: Kolbe, Lautemann, Ann. 115, 205 (1861); Spallino, Provenzal, Gazz. Chim. Ital. 39 (II), 326 (1909); Royer et al., Bull. Soc. Chim. Fr. 1955, 1421.
Properties: Monoclinic prismatic needles from water, mp 127°. Volatile with steam. One gram dissolves in 10 liters of water at 20°. Sol in alc, ether, chloroform, benzene, petr ether.
Melting point: mp 127°
Derivative Type: Sodium salt
Molecular Formula: C11H13NaO3
Molecular Weight: 216.21
Percent Composition: C 61.11%, H 6.06%, Na 10.63%, O 22.20%
Properties: White cryst mass, freely sol in water.
Derivative Type: Amide
Molecular Formula: C11H15NO2
Molecular Weight: 193.24
Percent Composition: C 68.37%, H 7.82%, N 7.25%, O 16.56%
Properties: Needles from alc, mp 137°, dec 205°. Sol in org solvents and in aq solns of sodium carbonate.
Melting point: mp 137°
Derivative Type: Acetonyl ester
Molecular Formula: C14H18O4
Molecular Weight: 250.29
Percent Composition: C 67.18%, H 7.25%, O 25.57%
Properties: Needles from alcohol, mp 75°. Sol in alcohol.
Melting point: mp 75°
Use: As salicylic acid and salicylates. |