Title: Potassium Iodide
CAS Registry Number: 7681-11-0
Trademarks: Jodid (Merck KGaA); Thyroblock (Horner); Thyrojod (Henning)
Molecular Formula: IK
Molecular Weight: 166.00
Percent Composition: I 76.45%, K 23.55%
Line Formula: KI
Literature References: Potassium iodide of commerce contains about 99.5% KI. Prepd from HI and KHCO3. Purification by melting in dry hydrogen: Lingane, Kolthoff, Inorg. Synth. 1, 163 (1939). Continuous electrolytic process for large scale industrial prepn: Morylott, Elkins, US 2989450 (1961 to Dow). Toxicity data: Hildebrandt, Arch. Exp. Pathol. Pharmakol. 96, 292 (1923). Use in the treatment of radiation poisoning resulting from a nuclear accident: W. K. Waterfall, Br. Med. J. 281, 988 (1980); Bull. N.Y. Acad. Med. 57, 395 (1981).
Properties: Colorless or white, cubical crystals, white granules, or powder. Slightly deliquescent in moist air; on long exposure to air becomes yellow due to liberation of iodine, and small quantities of iodate may be formed; light and moisture accelerate the decompn. Aq solns also become yellow in time due to oxidation, but a small amount of alkali prevents it. d 3.12. mp 680° (volatilizes at higher temp). One gram dissolves in 0.7 ml water, 0.5 ml boiling water, 22 ml alcohol, 8 ml boiling alcohol, 51 ml abs alcohol, 8 ml methanol, 75 ml acetone, 2 ml glycerol, about 2.5 ml glycol. Potassium iodide solns readily dissolve elemental iodine. The aq soln is neutral or, usually, slightly alkaline. pH: 7-9. 30 g KI with 21 ml water gives 30 ml of a saturated soln at 25°. Approx LD i.v. in rats: 285 mg/kg (Hildebrandt). Incompat. Alkaloidal salts, chloral hydrate, tartaric and other acids, calomel, potassium chlorate, metallic salts.
Melting point: mp 680° (volatilizes at higher temp)
Density: d 3.12
Toxicity data: Approx LD i.v. in rats: 285 mg/kg (Hildebrandt)
Use: Manuf photographic emulsions; in animal and poultry feeds to the extent of 10-30 parts per million; in table salt as a source of iodine and in some drinking water; also in anal. chemistry.
Therap-Cat: Antifungal; expectorant; iodine supplement.
Therap-Cat-Vet: In actinobacillosis, actinomycosis. For simple goiter. As expectorant. In iodine deficiency and in chronic poisoning with lead or mercury. Orally only, not by injection. Externally for treatment of bursal enlargements.
Keywords: Antifungal (Synthetic); Expectorant; Replenishers/Supplements; Iodine. |