Title: Propacetamol
CAS Registry Number: 66532-85-2
CAS Name: N,N-Diethylglycine 4-(acetylamino)phenyl ester
Additional Names: N,N-diethylglycine ester with 4¢-hydroxyacetanilide; 4-acetamidophenyl (diethylamino)acetate
Molecular Formula: C14H20N2O3
Molecular Weight: 264.32
Percent Composition: C 63.62%, H 7.63%, N 10.60%, O 18.16%
Literature References: Injectable prodrug of acetaminophen, q.v. Prepn and pharmacology: J. C. Cognacq, BE 854376; idem, US 4127671 (1977, 1978 both to Hexachimie). Clinical comparison with injectable aspirin: R. De Marneffe, L. Mokassa, C. R. Ther. Pharmacol. Clin. 3, 23 (1985). Clinical studies: P. Delacroix et al., Sem. Hop. 61, 2739 (1985); J. Modai, ibid. 62, 587 (1986).
Properties: Thick oil.
Derivative Type: Hydrochloride
CAS Registry Number: 66532-86-3
Manufacturers' Codes: UP-34101
Trademarks: Pro-Dafalgan (UPSA)
Molecular Formula: C14H20N2O3.HCl
Molecular Weight: 300.78
Percent Composition: C 55.90%, H 7.04%, N 9.31%, O 15.96%, Cl 11.79%
Properties: mp 228°. Sol in water.
Melting point: mp 228°
Therap-Cat: Analgesic; antipyretic.
Keywords: Analgesic (Non-Narcotic); Antipyretic. |