Title: Propyliodone
CAS Registry Number: 587-61-1
CAS Name: 3,5-Diiodo-4-oxo-1(4H)-pyridineacetic acid propyl ester
Additional Names: 3,5-diiodo-4-pyridone-N-acetic acid propyl ester; propyl 3,5-diiodo-4-pyridone-N-acetate; propiodone
Trademarks: Dionosil (Glaxo)
Molecular Formula: C10H11I2NO3
Molecular Weight: 447.01
Percent Composition: C 26.87%, H 2.48%, I 56.78%, N 3.13%, O 10.74%
Literature References: Prepn: Branscombe, GB 517382 (1940 to I.C.I.). Description: Tomich et al., Br. J. Pharmacol. 8, 166 (1953).
Properties: Crystals, dec 186-187°. Slightly sol in saline, serum. Solubility in water at 15°: 0.014 g/100 ml; at 35°: 0.020 g/100 ml; at 95°: 0.020 g/100 ml. LD50 i.v. in mice: 300 mg/kg (Tomich).
Toxicity data: LD50 i.v. in mice: 300 mg/kg (Tomich)
Therap-Cat: Diagnostic aid (radiopaque medium).
Keywords: Diagnostic Aid (Radiopaque Medium). |