Title: Pygeum Africanum Extract
CAS Registry Number: 85865-74-3
Trademarks: Tadenan (Debat)
Literature References: Extract from the bark of the tree Pygeum africanum Hook, also known as Prunus africana (Hook) F. Kalkm (Rosaceae-Amygdaleae), which is native to tropical Asia and Africa. Prepn: J. Debat, FR 1578711; idem, FR M6703; idem, US 3856946 (1969, 1969, 1974 all to Labs. du Debat). Pharmacology: L. Thieblot et al., Therapie 26, 575 (1971). Identification of 1-docosanol, q.v., as active principle: idem et al., ibid. 32, 99 (1977). Characterization of components: R. Longo, S. Tira, Farmaco Ed. Prat. 38, 287 (1983); E. M. Martinelli et al., J. High Resolut. Chromatogr. Chromatogr. Commun. 9, 106 (1986). Clinical study in BPH: A. Barlet et al., Wien. Klin. Wochenschr. 102, 667 (1990). Review of clinical experience: A. Ishani et al., Am. J. Med. 109, 654-664 (2000).
Therap-Cat: In treatment of micturitional disorders due to benign prostatic hypertrophy. |