Title: Sodium Nitroprusside
CAS Registry Number: 14402-89-2
CAS Name: Pentakis(cyano-C)nitrosylferrate(2-) disodium
Additional Names: sodium nitrosylpentacyanoferrate(III); sodium nitroferricyanide; sodium nitroprussiate
Trademarks: Nipruss (Schwarz)
Molecular Formula: C5FeN6Na2O
Molecular Weight: 261.92
Percent Composition: C 22.93%, Fe 21.32%, N 32.09%, Na 17.55%, O 6.11%
Line Formula: Na2[Fe(CN)5NO]
Literature References: Prepn: L. Playfair, Proc. Roy. Soc. London 5, 846 (1849). Pharmacology: Fernandez et al., Arch. Inst. Farmacol. Exp. Madrid 23, 1-51 (1971). Review: I. H. Tuzel, J. Clin. Pharmacol. 14, 494-503 (1974). Review of pharmacology, toxicology and therapeutic uses: J. H. Tinker, J. D. Michenfelder, Anesthesiology 45, 340 (1976). Comprehensive description: R. Rucki, Anal. Profiles Drug Subs. 6, 487-513 (1977); A. Bult et al., ibid. 15, 781-792 (1986). Clinical trial in critically ill patients with heart failure: U. N. Khot et al., N. Engl. J. Med. 348, 1756 (2003).
Derivative Type: Dihydrate
CAS Registry Number: 13755-38-9
Trademarks: Nipride (Roche); Nitropress (Abbott)
Properties: Ruby-red, practically odorless, transparent crystals. Sol in ~2.3 parts water, slightly in alcohol. Slowly dec in aq soln.
Use: Reagent for the detection of many organic compds, e.g., acetone, aldehydes, also of alkali sulfides, zinc, SO2.
Therap-Cat: Antihypertensive.
Keywords: Antihypertensive. |