Title: Teclozan
CAS Registry Number: 5560-78-1
CAS Name: N,N¢-[1,4-Phenylenebis(methylene)]-bis[2,2-dichloro-N-(2-ethoxyethyl)acetamide]
Additional Names: N,N¢-bis(ethoxyethyl)-N,N¢-bis(dichloroacetyl)-1,4-xylylenediamine; N,N¢-bis(dichloroacetyl)-N,N¢-bis(2-ethoxyethyl)-1,4-bis(aminomethyl)benzene; teclosan; teclosine; teclozine
Manufacturers' Codes: NSC-107433; Win-13146; Win-AM-13146
Trademarks: Falmonox (Winthrop)
Molecular Formula: C20H28Cl4N2O4
Molecular Weight: 502.26
Percent Composition: C 47.83%, H 5.62%, Cl 28.23%, N 5.58%, O 12.74%
Literature References: Prepn: Surrey, Mayer, J. Med. Pharm. Chem. 3, 409 (1961). Amebicidal activity and toxicity: Berberian et al., Am. J. Trop. Med. Hyg. 10, 503 (1961).
Properties: Crystals, mp 137.6-143.9°. LD50 orally in mice: >8000 mg/kg (Berberian).
Melting point: mp 137.6-143.9°
Toxicity data: LD50 orally in mice: >8000 mg/kg (Berberian)
Therap-Cat: Antiamebic.
Keywords: Antiamebic. |