Title: Thozalinone
CAS Registry Number: 655-05-0
CAS Name: 2-(Dimethylamino)-5-phenyl-4(5H)-oxazolone
Additional Names: 2-(dimethylamino)-5-phenyl-2-oxazolin-4-one; 5-phenyl-2-(dimethylamino)-2-oxazolin-4-one; tozalinone
Trademarks: Stimsen (Lederle)
Molecular Formula: C11H12N2O2
Molecular Weight: 204.23
Percent Composition: C 64.69%, H 5.92%, N 13.72%, O 15.67%
Literature References: Prepn: Hardy, Jr. et al., US 3037990 (1962 to Am. Cyanamid). Pharmacological studies: B. M. Bernstein, C. N. Latimer, Psychopharmacologia 12, 338 (l968); U. H. Lindberg, J. Pedersen, Acta Pharm. Suec. 5, 15 (1968). In treatment of Parkinsonism: W. D. Gray, C. E. Edward, US 3665075 (1972 to Am. Cyanamid).
Properties: Crystals from water, mp 133-136°.
Melting point: mp 133-136°
Therap-Cat: Antidepressant.
Keywords: Antidepressant. |