Title: TMD
CAS Registry Number: 60761-10-6
CAS Name: Decahydro-1,1,4a-trimethyl-2-naphthalenol
Additional Names: 1,1,10-trimethyl-trans-2-decalol; 4,4,10b-trimethyl-trans-decal-3b-ol
Molecular Formula: C13H24O
Molecular Weight: 196.33
Percent Composition: C 79.53%, H 12.32%, O 8.15%
Literature References: Prepn: B. Gaspert et al., J. Chem. Soc. 1958, 624; C. Djerassi, D. Marshall, J. Am. Chem. Soc. 80, 3986 (1958); T. G. Halsall et al., J. Chem. Soc. 1959, 2798; S. L. Mukherjee, P. C. Dutta, ibid. 1960, 67. Inhibitor of cholesterol biosynthesis: J. A. Nelson et al., J. Am. Chem. Soc. 100, 4900 (1978); T.-Y. Chang et al., J. Biol. Chem. 254, 11258 (1979).
Properties: Crystals, mp 60-65° (subl). Sol in alcohol; slightly sol in water.
Melting point: mp 60-65° (subl)
Derivative Type: d-Form
Properties: Crystals, mp 87-88° (subl). [a]D26 +15.9° (CHCl3).
Melting point: mp 87-88° (subl)
Optical Rotation: [a]D26 +15.9° (CHCl3)
Derivative Type: l-Form
Properties: Crystals, mp 87-88° (subl). [a]D26 -16.9° (CHCl3).
Melting point: mp 87-88° (subl)
Optical Rotation: [a]D26 -16.9° (CHCl3)
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