Title: Tromantadine
CAS Registry Number: 53783-83-8
CAS Name: 2-[2-(Dimethylamino)ethoxy]-N-tricyclo[3.3.1.13,7]dec-1-ylacetamide
Additional Names: N-1-adamantyl-N-[2-(dimethylamino)ethoxy]acetamide; 1-(dimethylaminoethoxyacetamido)adamantane
Molecular Formula: C16H28N2O2
Molecular Weight: 280.41
Percent Composition: C 68.53%, H 10.06%, N 9.99%, O 11.41%
Literature References: Prepn: Scherm, Peteri, DE 1941218 (1971 to Merz), C.A. 74, 99516k (1971); May, Peteri, Arzneim.-Forsch. 23, 718 (1973). Chemistry and toxicology: Peteri, Sterner, ibid. 577.
Derivative Type: Hydrochloride
CAS Registry Number: 41544-24-5
Manufacturers' Codes: D-41
Trademarks: Viru-Merz (Merz); Viruserol (Zyma)
Molecular Formula: C16H28N2O2.HCl
Molecular Weight: 316.87
Percent Composition: C 60.65%, H 9.22%, N 8.84%, O 10.10%, Cl 11.19%
Properties: Crystals, mp 157-158°. LD50 orally in rats: 630 mg/kg; i.v. in mice: 71.0 mg/kg (Peteri, Sterner).
Melting point: mp 157-158°
Toxicity data: LD50 orally in rats: 630 mg/kg; i.v. in mice: 71.0 mg/kg (Peteri, Sterner)
Therap-Cat: Antiviral.
Keywords: Antiviral. |