Title: Valpromide
CAS Registry Number: 2430-27-5
CAS Name: 2-Propylpentanamide
Additional Names: 2-propylvaleramide; 2-propylpentamide; dipropylacetamide
Trademarks: Depamide (Sanofi)
Molecular Formula: C8H17NO
Molecular Weight: 143.23
Percent Composition: C 67.08%, H 11.96%, N 9.78%, O 11.17%
Literature References: Prodrug of valproic acid, q.v. Prepn: E. Fischer, A. Dilthey, Ber. 35, 844 (1902); M. Tiffeneau, Y. Deux, Compt. Rend. 212, 105 (1941). GC determn in plasma: M. Pokrajac et al., Pharm. Acta Helv. 67, 237 (1992). Review of pharmacology and clinical activity: M. Bialer, Clin. Pharmacokinet. 20, 114-122 (1991).
Properties: White, odorless and bitter crystalline powder, mp 125-126°. Practically insol in water.
Melting point: mp 125-126°
Therap-Cat: Anticonvulsant.
Keywords: Anticonvulsant. |