Title: Vitamin B12, Radioactive
Additional Names: Radioactive cyanocobalamin; radiocyanocobalamin
Literature References: Prepn of 60Co labelled compound: Chaiet et al., Science 111, 601 (1950). Properties identical with unlabelled vitamin B12, except for the presence of radioactive cobalt. Evaluation of dual-isotope Schilling test for pernicious anemia: L. S. Zuckier, L. R. Chervu, J. Nucl. Med. 25, 1032 (1984).
Derivative Type: 60Co Vitamin B12
CAS Registry Number: 13422-53-2
Trademarks: Racobalamin-60 (Abbott); Rubratope-60 (BMS)
Properties: T½ 5.27 years, emitting beta and gamma rays.
Derivative Type: 58Co Vitamin B12
CAS Registry Number: 18195-32-9
Properties: T½ 70.8 days, emitting beta, gamma and x-rays.
Derivative Type: 57Co Vitamin B12
CAS Registry Number: 13115-03-2
Trademarks: Rubratope-57 (BMS)
Properties: T½ 271 days, emitting gamma and x-rays.
Derivative Type: Combination of 57Co and 58Co labelled Vitamin B12
Trademarks: Dicopac (Amersham)
Therap-Cat: Diagnostic aid (pernicious anemia).
Keywords: Diagnostic Aid. |