美国FDA药品溶出方法数据库

药品通用名称	剂型	USP溶出装置	速度	溶出介质	介质体积	建议取样时间（分钟）	更新日期
Acetaminophen/Caffeine/Dihydrocodeine Bitartrate	Tablet			Develop a dissolution method			2023/09/15
Acetaminophen/Hydrocodone Bitartrate	Tablet			Refer to USP (provide individual unit data).			2013/08/15
Acetaminophen/Ibuprofen	Tablet	II (Paddle)	50	50 mM Phosphate Buffer, pH 7.2	900	5, 10, 15, 20, and 30	2023/02/09
Acetaminophen/Oxycodone	Tablet			Refer to USP			2008/01/14
Acetaminophen/Oxycodone HCl	Tablet (Extended Release)	II (Paddle) with sinker	100	0.1 N HCl	900	0.25, 0.5, 1, 2, 4, 6 and 8 hours	2015/11/19
Acetaminophen/Pentazocine HCl	Tablet			Develop a dissolution method			2023/09/15
Acetaminophen/Tramadol HCl	Tablet	II (Paddle)	50	0.1 N HCl	900	5, 10, 15, 20 and 30	2006/03/04
Acetaminophen; Butalbital	Capsule			Develop a dissolution method			2024/02/05
Acetazolamide	Capsule (Extended Release)	II (Paddle)	75	Acetate Buffer, pH 4.5 with 2.2% Tween 20	900	1, 2, 5, 7, 9, 12 and 14 hours	2010/01/15
Acetazolomide	Tablet			Develop a dissolution method			2024/01/03
Acetylcysteine	Tablet (Effervescent)			Develop a dissolution method			2016/07/28
Acitretin	Capsule			Refer to USP			2011/09/22
Acrivastine/Pseudoephedrine HCl	Capsule	II (Paddle)	50	0.01 N HCl	900	5, 10, 15 and 30	2004/01/12
Acyclovir	Suspension	II (Paddle)	50	0.1 N HCl	900	10, 20, 30, 45 and 60	2004/02/20
Acyclovir	Tablet			Refer to USP			2007/06/18
Acyclovir	Capsule			Refer to USP			2012/01/05
Acyclovir	Tablet (Buccal)	I (Basket)	60	Phosphate Buffer, pH 6.0	1000	1, 2, 3, 5, 7, 9 and 12 hours	2015/08/27
Adagrasib	Tablet	II (Paddle)	75	pH 6.8 phosphate buffer with 0.3% SLS	900	10, 15, 30, 45 and 60	2024/02/05
Adefovir Dipivoxil	Tablet			Refer to FDA's Dissolution Guidance, 2018			2020/07/02
Afamelanotide	Implant			Develop a method to characterize in vitro release			2023/05/18