美国FDA药品溶出方法数据库

药品通用名称	剂型	USP溶出装置	速度	溶出介质	介质体积	建议取样时间（分钟）	更新日期
Tepotinib HCl	Tablet	II (Paddle)	50	Acetate buffer, pH 4.5 + 1 mM NaCl + 0.1% polysorbate 80	900	5, 15, 20 and 35	2023/03/30
Terazosin HCl	Tablet			Develop a dissolution method			2023/09/15
Terazosin HCl	Capsule			Develop a dissolution method			2023/09/15
Terbinafine HCl	Tablet	II (Paddle)	50	Citrate Buffer, pH 3.0 adjusted with HCl	500	10, 20, 30 and 45	2004/02/20
Terconazole	Suppository (Vaginal)	I (with Palmieri type basket)	100	0.12 N HCl with 1% SLS	900	15, 30, 45, 60, 90, 120 and 150	2009/10/08
Teriflunomide	Tablet	II (Paddle)	50	0.05 M Phosphate Buffer, pH 6.8	1000	5, 10, 15, 20, 30 and 45	2014/05/15
Testosterone	Film, Transdermal (Extended Release)	V (Paddle over disk). Paddle 25 mm above the film on the disk.	50	0.1 M sodium chloride containing 2.5% (v/v) of Tween 40 at 32 ± 0.5°C. Delivery surface faces upwards towards the media.	900	1, 3, 5, 7, 11, 16, 20 and 24 hours	2011/06/30
Testosterone	Buccal Tablet (Extended Release)			Develop a dissolution method			2023/09/15
Testosterone	Pellet Implant			Develop a dissolution method			2008/11/25
Testosterone Undecanoate	Capsule	II (Paddle)	75	0.01 N HCl with 0.5% Triton X 100	900	5, 10, 15, 30, 45 and 60	2024/02/05
Testosterone Undecanoate	Capsule	II (Paddle)	75	Phosphate buffer pH 6.8 with 1.0% Triton X-100	900	10, 15, 20, 30 and 45	2021/08/19
Tetrabenazine	Tablet	II (Paddle)	50	0.1 N HCl	900	5, 10, 15, 30 and 45	2011/09/01
Tetracycline HCl	Tablet			Refer to FDA's Dissolution Guidance, 2018			2020/07/02
Tetracycline HCl	Capsule			Refer to FDA's Dissolution Guidance, 2018			2020/07/02
Thalidomide	Capsule	II (Paddle)	100	1.5% (w/v) SLS (pH 3.0, adj w/ HCl)	900	10, 20, 30, 60 and 90	2006/03/04
Theophylline	Capsule (Extended Release)			Refer to USP	900		2008/10/06
Theophylline (100 mg and 200 mg)	Tablet (Extended Release)	II (Paddle)	50	SGF without Enzyme, pH 1.2 during 1st hour. Phosphate Buffer at pH 7.5 from end of hour 1 through the duration of testing	900	1, 4, 8, 12 hours	2008/10/06
Theophylline (300 mg and 450 mg)	Tablet (Extended Release)	II (Paddle)	50	SGF without Enzyme, pH 1.2 during 1st hour. Phosphate Buffer at pH 7.5 from end of hour 1 through the duration of testing	900	1, 4, 8, 12 hours	2008/10/06
Theophylline (600 mg and 400 mg)	Tablet (Extended Release)	I (Basket)	100	SGF without enzyme, pH 1.2 during 1st hour. SIF without enzyme from end of hour 1 through the duration of the testing	900	1, 2, 4, 8, 12 and 24 hours	2008/10/06
Thioguanine	Tablet			Develop a dissolution method			2024/01/03