美国FDA药品溶出方法数据库

药品通用名称	剂型	USP溶出装置	速度	溶出介质	介质体积	建议取样时间（分钟）	更新日期
Tranexamic Acid	Tablet			Develop a dissolution method			2023/09/15
Tranylcypromine Sulfate	Tablet			Refer to FDA's Dissolution Guidance, 2018			2020/07/02
Trazodone HCl	Tablet			Refer to USP			2023/05/18
Trazodone HCl	Tablet (Extended Release)			Develop a dissolution method			2023/09/15
Treprostinil Diolamine	Tablet (Extended Release)	I (Basket)	100	0.05 M Phosphate Buffer, pH 6.8 (deaerated)	500	1, 2, 4, 6, 8, 12, 16, 20 and 24 hours	2016/06/02
Tretinoin	Capsule	I (Basket)	100	0.5% solid Lauryldimethylamine-oxide (LDAO) in 0.05M Phosphate Buffer, pH 7.8	900	10, 15, 20, 30 and 45	2010/08/05
Triamcinolone Acetonide	Intra-Articular, For Suspension (Extended Release)	II (Paddle)	75	0.3% SDS in 10 mM phosphate buffer, pH 7.2 + 0.02% sodium azide @35°C	1000	1, 2, 4, 8, 12, 16, 24, 36, 48, 72, 96 and 120 hours	2018/02/08
Triamcinolone Acetonide	Injectable Suspension			Develop a dissolution method using USP IV (Flow-Through Cell), and, if applicable, Apparatus II (Paddle) or any other appropriate method, for comparative evaluation by the Agency			2010/01/15
Triclabendazole	Tablet	II (Paddle)	75	0.1N HCl with 1% Tween 20	1000	5, 10, 15, 20 and 30	2020/08/27
Trientine HCl	Capsule			Refer to FDA's Dissolution Guidance, 2018			2020/07/02
Trimethoprim	Tablet			Refer to USP			2010/01/29
Trimipramine Maleate	Capsule			Refer to FDA's Dissolution Guidance, 2018			2020/07/02
Triptorelin Pamoate	For Intramuscular Suspension (Extended Release)	II (Paddle)	75	50 mL of methanol to 950 mL of water	950	1, 8, 24, 96, and 168 hours	2017/11/16
Triptorelin Pamoate	Injectable Suspension	II (Paddle)	200	Water-Methanol (95:5); Reconstitute vial in 2 mL Water for Injection, add to 500 mL medium at 37°C	500	1, 6, 12, 24, 48 and 72 hours	2008/07/14
Trospium Chloride	Capsule (Extended Release)	II (Paddle) with sinker	50	0.1 N HCl, pH 1.1 for 2 hrs and then add 200 mL of 0.1 N NaOH in 200 mM Phosphate Buffer. Adjust pH to 7.5 using 2 N HCl and/or 2N NaOH	0-2 hrs: 750 ml, After 2 hrs: 950 ml.	2, 3, 4, 6, 8, 12 and 16 hours	2010/07/15
Trospium Chloride	Tablet			Refer to FDA's Dissolution Guidance, 2018			2020/07/02
Tucatinib	Tablet	II (Paddle)	75	0.1 M Citrate Buffer, pH 3.4, containing 0.05% Brij 35 (polyoxyethylene lauryl ether)	900	10, 15, 20, 30 and 45	2022/05/12
Ulipristal Acetate	Tablet	II (Paddle)	50	0.1 N HCl	900	5, 10, 15, 20 and 30	2013/01/31
Upadacitinib	Tablet (Extended Release)	I (Basket)	100	50 mM Phosphate buffer, pH 6.8 [for 15 mg and 30 mg strengths]; 25 mM Phosphate buffer with 2.75% NaCl, pH 6.8 for [45 mg strength]	900	1, 2, 4, 6, 8, 12 and 16 hours	2023/02/09
Uridine Triacetate	Granule	II (Paddle)	60	50 mM Phosphate Buffer, pH 6.8	900	10, 15, 20, 30, 45 and 60	2022/07/07