Octenidine hydrochloride, Win-414642-药物合成数据库

【药物名称】Octenidine hydrochloride, Win-414642

化学结构式(Chemical Structure):

参考文献No.	49605
标题:	Octenidine hydrochloride
作者:	Casta馿r, J.; Pento, J.T.
来源:	Drugs Fut 1986,11(4),269

合成路线图解说明: The condensation of octylamine (I) with 4-bromopyridine by heating at 180 C gives (4-octylamino)piridine (III), which is then allowed to react with 1,10-dichlorodecane by heating 120-80 C.

参考文献No.	555594
标题:	Bispyridinamines: A new class of topical antimicrobial agents as inhibitors of dental plaque
作者:	Bailey, D.M.; DeGrazia, C.G.; Hoff, S.J.; Schulenberg, P.L.; O'Connor, J.R.; Paris, D.A.; Slee, A.M.
来源:	J Med Chem 1984,27(11),1457

合成路线图解说明: The condensation of octylamine (I) with 4-bromopyridine by heating at 180 C gives (4-octylamino)piridine (III), which is then allowed to react with 1,10-dichlorodecane by heating 120-80 C.