Lodaxaprine, CM-40907-药物合成数据库

【药物名称】Lodaxaprine, CM-40907

化学结构式(Chemical Structure):

参考文献No.	49638
标题:	CM-40907
作者:	L鰏cher, W.
来源:	Drugs Fut 1985,10(11),903

合成路线图解说明: 3-(4-Hydroxypiperidino)-6-(2-chlorophenyl)pyridazine (CM-40907) is synthesized from 3-chloro-6-(2-chlorophenyl)pyridazine (I) in boiling 1-butanol (A) with an excess of 4-hydroxypiperidine (II).

参考文献No.	607997
标题:	CM 40907: A structurally novel anticonvulsant in mice, rats and baboons
作者:	Chambon, J.P.; Brochard, J.; Hallot, A.; Heaulme, M.; Brodin, R.; Roncucci, R.; Bizi鑢e, K.
来源:	J Pharmacol Exp Ther 1985,233(3),836-844

合成路线图解说明: 3-(4-Hydroxypiperidino)-6-(2-chlorophenyl)pyridazine (CM-40907) is synthesized from 3-chloro-6-(2-chlorophenyl)pyridazine (I) in boiling 1-butanol (A) with an excess of 4-hydroxypiperidine (II).