Merafloxacin, CI-934-药物合成数据库

【药物名称】Merafloxacin, CI-934

化学结构式(Chemical Structure):

参考文献No.	1383
标题:	Antibacterial agents
作者:	Culbertson, T.P.; Mich, T.F.; Domagala, J.M.; Nichols, J.B. (Pfizer Inc.)
来源:	EP 0106489; ES 8600934; JP 1989146880

合成路线图解说明: By condensation of 1-ethyl-6,7,8-trifluoro-1,4-dihydro-4-oxoquinoline-3-carboxilic acid (I) with 3-(ethylaminomethyl)pyrrolidone (II) by means of 1,8-diazabicyclo[5.4.0]undec-7-ene (DBU) in acetonitrile.

参考文献No.	51197
标题:	CI-934
作者:	Prous, J.; Casta馿r, J.
来源:	Drugs Fut 1986,11(5),366

合成路线图解说明: By condensation of 1-ethyl-6,7,8-trifluoro-1,4-dihydro-4-oxoquinoline-3-carboxilic acid (I) with 3-(ethylaminomethyl)pyrrolidone (II) by means of 1,8-diazabicyclo[5.4.0]undec-7-ene (DBU) in acetonitrile.