Benzquinamide, NSC-224070, BZQ, Emete-Con-药物合成数据库

【药物名称】Benzquinamide, NSC-224070, BZQ, Emete-Con

化学结构式(Chemical Structure):

参考文献No.	62051
标题:	BZQ
作者:	Bosanquet, A.G.
来源:	Drugs Fut 1986,11(1),12

合成路线图解说明: Ethyleneimine is reacted with tetrafluoro-1.4-benzoquinone (I) in the cold to form 2,5-diaziridinyl-3,6-difluoro-1-4-benzoquinone (II). The reaction with ethanolamine at room temperature results in BZQ, which is recrystallized from ethanol.

参考文献No.	555583
标题:	Potential central nervous system antitumor agents. Aziridinylbenzoquinones
作者:	Chou, F.; Khan, A.H.; Driscoll, J.S.
来源:	J Med Chem 1976,19(11),1302

合成路线图解说明: Ethyleneimine is reacted with tetrafluoro-1.4-benzoquinone (I) in the cold to form 2,5-diaziridinyl-3,6-difluoro-1-4-benzoquinone (II). The reaction with ethanolamine at room temperature results in BZQ, which is recrystallized from ethanol.