Brequinar sodium, NSC-368390, DuP-785-药物合成数据库

【药物名称】Brequinar sodium, NSC-368390, DuP-785

化学结构式(Chemical Structure):

参考文献No.	960
标题:	Phenylquinolinecarboxylic acids and derivatives as antitumor agents
作者:	Hesson, D.P. (DuPont Pharmaceuticals Co.)
来源:	AU 8430852; EP 0133244; JP 8542367; US 4680299

合成路线图解说明: By cyclization of 5-fluoroisatin (I) with 4-(2-fluorophenyl)- propiophenone (II) by means of NaOH in refluxing ethanol - water.

参考文献No.	62378
标题:	BREQUINAR SODIUM < Prop INNM >
作者:	Eastland, G. Jr.; Prous, J.; Casta馿r, J.
来源:	Drugs Fut 1988,13(1),13

合成路线图解说明: By cyclization of 5-fluoroisatin (I) with 4-(2-fluorophenyl)- propiophenone (II) by means of NaOH in refluxing ethanol - water.