Cyanidin chloride monohydrate, IdB-1027, Gastrotelos-药物合成数据库

【药物名称】Cyanidin chloride monohydrate, IdB-1027, Gastrotelos

化学结构式(Chemical Structure):

参考文献No.	46446
标题:	Process for the synthesis of anthocyanidines and novel intermediates produced in said processes
作者:	Gabetta, B.; Giorgi, R.; Pifferi, G. (Incyte Pharmaceuticals, Inc.)
来源:	EP 0348121; ES 2053992T; JP 2040376; PT 90920

合成路线图解说明: Condensation of 2,4-di-O-benzoylphloroglucinaldehyde (I) with omega-acetoxy-3,4-diacetoxyacetophenone (II) in the presence of HCl gives the 5,7-dibenzoyloxy-3-hydroxy-2-(3,4-dihydroxyphenyl)-1-benzopyrylium chloride (III), which is subsequently hydrolyzed with NaOH and finally treated with HCl.

参考文献No.	85083
标题:	IdB-1027
作者:	Magistretti, M.J.; Pifferi, G.
来源:	Drugs Fut 1989,14(3),224

合成路线图解说明: Condensation of 2,4-di-O-benzoylphloroglucinaldehyde (I) with omega-acetoxy-3,4-diacetoxyacetophenone (II) in the presence of HCl gives the 5,7-dibenzoyloxy-3-hydroxy-2-(3,4-dihydroxyphenyl)-1-benzopyrylium chloride (III), which is subsequently hydrolyzed with NaOH and finally treated with HCl.