【药物名称】Nimodipine, Bay-e-9736, Periplum, Admon, Nimotop
化学结构式(Chemical Structure):
参考文献No.53408
标题:Nimodipine
作者:Casta馿r, J.; Serradell, M.N.; Mealy, N.E.; Blancafort, P.; Leeson, P.A.
来源:Drugs Fut 1981,6(2),98
合成路线图解说明:

By cyclocondensation of a mixture of isopropyl(m-nitrobenzylidene)acetylacetate (II), 2-methoxyethyl acetylacetate (I) and NH3 in refluxing ethanol.

参考文献No.700847
标题:Unsymmetrical esters of 1,4-dihydropyridine-3,5-dicarboxylic acid
作者:Meyer, H.; et al.
来源:BE 0781878; DE 2117571; FR 2132830; GB 1358951; US 3799934
合成路线图解说明:

By cyclocondensation of a mixture of isopropyl(m-nitrobenzylidene)acetylacetate (II), 2-methoxyethyl acetylacetate (I) and NH3 in refluxing ethanol.

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