Verapamil, Calan, Securon, Cordilox, Verelan PM, Chronovera, Covera-HS(controlled onset, extended release system), Isoptin(HCl)-药物合成数据库

【药物名称】Verapamil, Calan, Securon, Cordilox, Verelan PM, Chronovera, Covera-HS(controlled onset, extended release system), Isoptin(HCl)

化学结构式(Chemical Structure):

参考文献No.	50944
标题:	Basically substd. phenyl acetonitrile cpds.
作者:	Dengel, F. (Knoll AG)
来源:	US 3261859

合成路线图解说明: The condensation of 2-(3,4-dimethoxyphenyl)-3-methylbutyronitrile (I) with N-(3-chloropropyl)-N-[2-(3,4-dimethoxyphenyl)ethyl]-N-methylamine (II) by means of sodium amide in refluxing toluene gives the target aminonitrile.