【药物名称】Carboplatin, NSC-241240, JM-8, CBDCA, Ercar, Paraplatin
化学结构式(Chemical Structure):
参考文献No.55727
标题:Carboplatin
作者:Serradell, M.N.; Blancafort, P.; Casta馿r, J.; Hopkins, S.J.
来源:Drugs Fut 1983,8(6),489
合成路线图解说明:

The reaction of cis-diammine-platinum diiodide (I) with silver sulfate (II) gives cis-diaquo-diammine-platinum sulfate (III), which is then treated with barium cyclobutane-1,1-dicarboxylate (IV).

参考文献No.800100
标题:An efficient route for the preparation of highly soluble platinum (II) antitumor agents
作者:Zaki, A.M.; Harrison, R.C, McAuliffe, C.M.
来源:Inorg Chim Acta 1980,46(1),L15-16
合成路线图解说明:

The reaction of cis-diammine-platinum diiodide (I) with silver sulfate (II) gives cis-diaquo-diammine-platinum sulfate (III), which is then treated with barium cyclobutane-1,1-dicarboxylate (IV).

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