BE-6143, BDF-6143-药物合成数据库

【药物名称】BE-6143, BDF-6143

化学结构式(Chemical Structure):

参考文献No.	46042
标题:	Hypotensive 2-heterocycloaminoimidazolines
作者:	Cohnen, E. (Beiersdorf-Lilly GmbH)
来源:	DE 2816627; DE 2905501; FR 2423491; GB 2021100; JP 79151990; US 4221798

合成路线图解说明: By condensation of 4-chloro-2-aminoisoindoline (I) with 1-acetylimidazolidin-2-one (II) by means of POCl3 at 100 C, followed by hydrolysis of the acetyl group with hot ethanol.

参考文献No.	57058
标题:	BDF-6143
作者:	Casta馿r, J.; Serradell, M.N.
来源:	Drugs Fut 1984,9(2),100

合成路线图解说明: By condensation of 4-chloro-2-aminoisoindoline (I) with 1-acetylimidazolidin-2-one (II) by means of POCl3 at 100 C, followed by hydrolysis of the acetyl group with hot ethanol.