Trombodipine, PCA-4230-药物合成数据库

【药物名称】Trombodipine, PCA-4230

化学结构式(Chemical Structure):

参考文献No.	7614
标题:	1,4-Dihydropyridines, processes for their preparation and their use as antithrombotic drugs
作者:	Sunkel, C.; Fau de Casa-Juana, M.; Dorrego, F.; Priego, J.; Ortega, P.; Cillero, J. (Alter SA)
来源:	DE 3617976; EP 0253092; US 4782069

合成路线图解说明: The reaction between acetaldehyde (I), ethyl 3-aminocrotonate (II) and acetoacetate (III) in ethanolic medium yields the corresponding 1,4-dihydropyridine.

参考文献No.	175816
标题:	Trombodipine
作者:	Ortega, M.P.; Priego, J.G.; Fau de Casa-Juana, M.; Cillero, F.J.; Sunkel, C.E.
来源:	Drugs Fut 1992,17(6),465

合成路线图解说明: The reaction between acetaldehyde (I), ethyl 3-aminocrotonate (II) and acetoacetate (III) in ethanolic medium yields the corresponding 1,4-dihydropyridine.