Enalapril maleate, MK-421, Ednit, Ditensor, Dabonal, Baripril, Crinoren, Xanef, Renitec, Enapren, Innovace, Innovace Melt(freeze-dried oral wafer), Lexxel(comb. with felodipine), Renivace, Vasotec-药物合成数据库

【药物名称】Enalapril maleate, MK-421, Ednit, Ditensor, Dabonal, Baripril, Crinoren, Xanef, Renitec, Enapren, Innovace, Innovace Melt(freeze-dried oral wafer), Lexxel(comb. with felodipine), Renivace, Vasotec

化学结构式(Chemical Structure):

参考文献No.	57473
标题:	Enalapril maleate
作者:	Hopkins, S.J.; Serradell, M.N.; Blancafort, P.; Casta馿r, J.
来源:	Drugs Fut 1982,7(8),556

合成路线图解说明: By reductocondensation of ethyl 2-oxo-4-phenylbutyrate (I) with alanylproline (II) by means of sodium cyanoborohydride or H2 over Raney-Ni or Pd/C in water.

参考文献No.	800198
标题:	A new class of angiotensin-converting anzyme inhibitors
作者:	Patchett, A.A.; et al.
来源:	Nature 1980,288280-283

合成路线图解说明: By reductocondensation of ethyl 2-oxo-4-phenylbutyrate (I) with alanylproline (II) by means of sodium cyanoborohydride or H2 over Raney-Ni or Pd/C in water.