【药物名称】P-0285
化学结构式(Chemical Structure):
参考文献No.8641
标题:Dihydropyridines with an antagonistic activity to
作者:Zumin Tricerri, S.; Casagrande, C.; De Marchi, F.; Nicola, M. (Pierrel SpA)
来源:EP 0097821; US 4894460
合成路线图解说明:

Hantzsch condensation of 2-[4-(3,4-dichlorophenyl)piperazin-1-yl]ethyl acetylacetate (III) with methyl 3-aminocrotonate (II) and 3-nitrobenzaldehyde (I) in eftuxing isopropanol affords title compound.

参考文献No.62400
标题:P-0285
作者:Bani, M.; Favara, D.
来源:Drugs Fut 1988,13(4),321
合成路线图解说明:

Hantzsch condensation of 2-[4-(3,4-dichlorophenyl)piperazin-1-yl]ethyl acetylacetate (III) with methyl 3-aminocrotonate (II) and 3-nitrobenzaldehyde (I) in eftuxing isopropanol affords title compound.

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