HWA-153, A-730153-药物合成数据库

【药物名称】HWA-153, A-730153

化学结构式(Chemical Structure):

参考文献No.	701408
标题:
作者:	Stefanovich, V.
来源:	Private Communication 2002,10(9),3001

合成路线图解说明: By treating 3-methylxanthine (I) with sodium hydroxide and 1-bromo-5-hexanone (II) to give 3-methyl-7-(5-oxohexyl)xanthine (III), which is reacted to (IV) with 1-bromopropane (A) in the same way. Compound (IV) is reduced to the title compound with sodium borohydride.

参考文献No.	800482
标题:	HWA-153
作者:	Unterhalt, B.
来源:	Drugs Fut 1980,5(2),77

合成路线图解说明: By treating 3-methylxanthine (I) with sodium hydroxide and 1-bromo-5-hexanone (II) to give 3-methyl-7-(5-oxohexyl)xanthine (III), which is reacted to (IV) with 1-bromopropane (A) in the same way. Compound (IV) is reduced to the title compound with sodium borohydride.