【药物名称】Temoporfin, KW-2345, EF9, mTHPC, Foscan
化学结构式(Chemical Structure):
参考文献No.11308
标题:Porphyrins and cancer treatment
作者:Bonnett, R.; Berenbaum, M.C. (Efamol Holdings plc)
来源:AU 8930975; EP 0337601; JP 1989275528; US 4992257; US 5162519
合成路线图解说明:

Tetra(m-hydroxyphenyl)porphyrin (I) was reduced with diimide, generated in situ from tosyl hydrazide in the presence of K2CO3 and pyridine. The resulting mixture containing dihydro- and tetrahydroporphyrins was then reoxidized by means of o-chloranil to produce the desired dihydro compound.

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