【药物名称】Isbufylline, TE-06
化学结构式(Chemical Structure):
参考文献No.12008
标题:Xanthine derivs., pharmaceutical compsns. containing same and their therapeutic use
作者:Fedi, M.; Bonacchi, G. (Malesci Ist. Farmacobiol. SpA)
来源:US 4544556
合成路线图解说明:

By reaction of theophylline sodium salt with isobutyl halogenide in N,N-dimethylformamide at 80 C.

参考文献No.106578
标题:Crystal structure of a new antibronchospastic drug: 1,3-dimethyl-7-isobutylxanthine (TE 06)
作者:Bonacchi, G.; Manzini, S.; Dapporto, P.; Paoli, P.
来源:In: Three-Dimensional Molecular Structure and Drug Action - 15th Course of International School of Crystallography (June 1-11, Erice) 1989,Poster No. 8
合成路线图解说明:

By reaction of theophylline sodium salt with isobutyl halogenide in N,N-dimethylformamide at 80 C.

参考文献No.115232
标题:ISBUFYLLINE
作者:Manzini, S.; Fedi, M.; Bonacchi, G.; Agostini, O.
来源:Drugs Fut 1990,15(3),228
合成路线图解说明:

By reaction of theophylline sodium salt with isobutyl halogenide in N,N-dimethylformamide at 80 C.

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