Limazocic, SA-3443-药物合成数据库

【药物名称】Limazocic, SA-3443

化学结构式(Chemical Structure):

参考文献No.	13489
标题:	Cyclic sulfur-containing cpds
作者:	Morita, T.; Mita, S.; Iso, T.; Kawashima, Y. (Santen Pharmaceutical Co., Ltd.)
来源:	EP 0356006; US 5041435

合成路线图解说明: By oxidative cyclization of N-(3-mercapto-2,2-dimethylpropionyl)-L-cysteine (I) by means of I2 in dichloromethane, diethyl bromomalonate and triethylamine in the same solvent.

参考文献No.	179266
标题:	SA-3443
作者:	Prous, J.; Casta馿r, J.
来源:	Drugs Fut 1992,17(7),566

合成路线图解说明: By oxidative cyclization of N-(3-mercapto-2,2-dimethylpropionyl)-L-cysteine (I) by means of I2 in dichloromethane, diethyl bromomalonate and triethylamine in the same solvent.