Balofloxacin dihydrate, Q-35, Baloxin, Neuroquinoron-药物合成数据库

【药物名称】Balofloxacin dihydrate, Q-35, Baloxin, Neuroquinoron

化学结构式(Chemical Structure):

参考文献No.	11543
标题:	Novel quinolinecarboxylic acid derivatives
作者:	Nagano, H.; Yokota, T.; Katoh, Y. (Chugai Seiyaku Co., Ltd.)
来源:	EP 0342675; JP 91095177

合成路线图解说明: By reaction of 1-cyclopropyl-6,7-difluoro-8-methoxy-4-oxo-1,4-dihydroquinoline-3-carboxylic acid (I) with 3-(methylamino)piperidine (II) by means of triethylamine in refluxing acetonitrile.

参考文献No.	173738
标题:	Q-35
作者:	Prous, J.; Casta馿r, J.
来源:	Drugs Fut 1992,17(5),382

合成路线图解说明: By reaction of 1-cyclopropyl-6,7-difluoro-8-methoxy-4-oxo-1,4-dihydroquinoline-3-carboxylic acid (I) with 3-(methylamino)piperidine (II) by means of triethylamine in refluxing acetonitrile.