Pivagabine, Tonerg-药物合成数据库

【药物名称】Pivagabine, Tonerg

化学结构式(Chemical Structure):

参考文献No.	453773
标题:	Pivagabine
作者:	Esposito, G.; Lazzarini, R.
来源:	Drugs Fut 1998,23(4),390

合成路线图解说明: Pivagabine is prepared by reacting pivaloyl chloride (I) and 4-aminobutyric acid (II) in aqueous sodium hydroxide solution; by adding dilute hydrochloric acid the crude product is isolated and then purified by crystallization from water.

参考文献No.	604461
标题:	Adjustment disorder as a marginal or transitional illness category in DSM-III
作者:	Mezzich, J.E.; Mezzich, A.C.; Fabrega, H.
来源:	Arch Gen Psychiatry 1987,44(6),567-72

合成路线图解说明: Pivagabine is prepared by reacting pivaloyl chloride (I) and 4-aminobutyric acid (II) in aqueous sodium hydroxide solution; by adding dilute hydrochloric acid the crude product is isolated and then purified by crystallization from water.