Pumosetrag hydrochloride, MKC-733-药物合成数据库

【药物名称】Pumosetrag hydrochloride, MKC-733

化学结构式(Chemical Structure):

参考文献No.	21864
标题:	Thieno[3,2-b]pyridine derivs. for the treatment of gastrointestinal disorders
作者:	Maruyama, A.; Ogawa, S.; Yamazaki, S.; Tobe, A. (Mitsubishi Chemical Corp.)
来源:	EP 0560348; JP 1993310747; US 5352685

合成路线图解说明: MKC-733 is synthesized by condensation of 7-oxo-4,7-dihydrothieno[3,2-b]pyridine-6-carboxylic acid (I) with quinuclidin-3(R)-amine (II) by means of carbonyldimidazole in DMF.

参考文献No.	489134
标题:	MKC-733
作者:	Rabasseda, X.; Casta馿r, J.; Revel, L.
来源:	Drugs Fut 1999,24(9),966

合成路线图解说明: MKC-733 is synthesized by condensation of 7-oxo-4,7-dihydrothieno[3,2-b]pyridine-6-carboxylic acid (I) with quinuclidin-3(R)-amine (II) by means of carbonyldimidazole in DMF.