【药物名称】YM-31636
化学结构式(Chemical Structure):
参考文献No.23481
标题:Novel condensed thiazole deriv., process for producing the same, and pharmaceutical compsn. containing the same
作者:Iwaoka, K.; Koshio, H.; Ito, H.; Miyata, K.; Ohta, M. (Yamanouchi Pharmaceutical Co., Ltd.)
来源:EP 0666263; JP 1995507965; US 5565479; WO 9406791
合成路线图解说明:

The title compound is prepared by condensation between 2-bromo-1-indanone (I) and 2-(4-imidazolyl)thioacetamide hydrochloride (II) in refluxing isopropanol, followed by treatment with fumaric acid in MeOH.

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