The reaction of 3-[1-(triphenylmethyl)imidazol-4-yl]propionaldehyde (I) with carbon tetrabromide by means of lithium dicyclohexylamine gives 1,1-dibromo-4-[1-(triphenylmethyl)imidazol-4-yl]-2-butanol (II), which is treated with methanesulfonyl chloride in THF to yield the corresponding mesylate (III). The elimination reaction over (III) with triethylamine affords 1,1-dibromo-4-[1-(triphenylmethyl)imidazol-4-yl]-1-butene (IV), which by tretment with butyllithium in THF gives 4-[1-(triphenylmethyl)imidazol-4-yl]-1-butyne (V). The condensation of (V) with 2-cyclohexylethyl iodide (VI) by means of butyllithium and tetramethylethylenediamine (TEMDA) gives the 3-hexyne derivative (VII), which is finally deprotected with HCl in hot ethanol.