Enediyne compound (I) as an unseparable 2:1 mixture of diastereoisomers was hydrolyzed with barium hydroxide in methanol-dichloromethane at 0 C to provide a mixture of alcohols (II), which were immediately converted into carbonyl imidazole intermediates (III) by treatment with carbonyldiimidazole (CDI) and 4-(dimethylamino)pyridine (DMAP) in cold dichloromethane. Reaction of (III) with an excess of 2-(1-pyrrolidinyl)ethylamine (IV) in dichloromethane at 0 C yielded a 2:1 mixture of diastereoisomeric carbamates, which on treatment with 0.01 M HCl gave the corresponding hydrochlorides.