【药物名称】BMOV
化学结构式(Chemical Structure):
参考文献No.23690
标题:Complexed vanadium for the treatment of diabetes mellitus
作者:McNeill, J.H.; Hoveyda, H.R.; Orvig, C. (University of British Columbia)
来源:JP 1994511244; US 5300496; WO 9306811
合成路线图解说明:

Bis(maltolato)oxovanadium(IV) is prepared by complexation of maltol (I) with vanadyl sulfate in refluxing aqueous solution, adjusting the pH at approx. 8.5 with KOH.

参考文献No.424149
标题:Reaction chemistry of BMOV, bis(maltolato) oxovanadium(IV), a potent insulin mimetic agent
作者:Orvig, C.; et al.
来源:J Am Chem Soc 1995,117(51),12759
合成路线图解说明:

Bis(maltolato)oxovanadium(IV) is prepared by complexation of maltol (I) with vanadyl sulfate in refluxing aqueous solution, adjusting the pH at approx. 8.5 with KOH.

参考文献No.714227
标题:Bis(maltolato)oxovanadium(IV) is a potent insulin mimic
作者:McNeill, J.H.; Yuen, V.G.; Hoveyda, H.R.; Orvig, C.
来源:J Med Chem 1992,35(8),1489
合成路线图解说明:

Bis(maltolato)oxovanadium(IV) is prepared by complexation of maltol (I) with vanadyl sulfate in refluxing aqueous solution, adjusting the pH at approx. 8.5 with KOH.

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