Reaction of 2,5-dibromopyridine (I) with an excess of 1,3-diaminopropane (II) in refluxing pyridine provided N-1-(2-pyridyl)propanediamine (III). This compound was further alkylated at the 1N with 3,4-dichlorobenzyl chloride (IV) in DMSO using NaH as the base to afford (V). From this, isothiocyanate (VI) was prepared by reaction with CS2 and DCC in THF. Subsequent coupling with trityl-protected amine (VII) yielded the thiourea (VIII). Finally, the trityl protecting group was removed by refluxing in 1 N HCl.