PP1D-1-药物合成数据库

【药物名称】PP1D-1

化学结构式(Chemical Structure):

参考文献No.	467199
标题:	Synthesis and cytotoxicity of 1,2-disubstituted naphth[2,3-d]imidazole-4,9-diones and related compounds
作者:	Kuo, S.-C.; Ibuka, T.; Huang, L.J.; Lien, J.C.; Yean, S.R.; Huang, S.C.; Lednicer, D.; Morris-Natschke, S.L.; Lee, K.H.
来源:	J Med Chem 1996,39(7),1447-1451

合成路线图解说明: Title compound was obtained by acylation of 2-amino-3-chloro-1,4-naphthoquinone (I) with 3-carbomethoxypropionyl chloride (II) in the presence of dry HCl in refluxing toluene.