-药物合成数据库

【药物名称】

化学结构式(Chemical Structure):

参考文献No.	461802
标题:	Synthesis of new thieno[2,3-d]pyrimidine-2,4(1H, 3H)-diones with analgesic and anti-inflammatory activities
作者:	Romeo, G.; et al.
来源:	Arzneim-Forsch Drug Res 1998,48(2),167-172

合成路线图解说明: Condensation of aminothiophene (I) with cyclohexyl isocyanate (II) in refluxing toluene afforded urea (III). Then, treatment with ethanolic KOH gave the pyrimidine dione system.