| 参考文献No. | 33848 |
| 标题: | Heterocycle-condensed morphinoid derivs. (II) |
| 作者: | Dondio, G.; Ronzoni, S.; Gatti, P.A.; Graziani, D. (SmithKline Beecham SpA) |
| 来源: | EP 0880526; JP 2000503019; WO 9725331 |
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| 合成路线图解说明: The compound was prepared by condensation of dihydrocodeinone hydrochloride (I) with N-Benzyl-N-isopropyl-2-(phenylhydrazono)-3-oxobutyramide (II) in the presence of zinc dust and NaOAc in refluxing AcOH. |
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| 合成路线图解说明: The compound was prepared by condensation of dihydrocodeinone hydrochloride (I) with N-Benzyl-N-isopropyl-2-(phenylhydrazono)-3-oxobutyric acid isobutyl ester (II) (II) in the presence of zinc dust and NaOAc in refluxing AcOH. |