【药物名称】PH-104
化学结构式(Chemical Structure):
参考文献No.478970
标题:Antileishmanial chalcones: Statistical design, synthesis, and three-dimensional quantitative structure-activity relationship analysis
作者:Nielsen, S.F.; Christensen, S.B.; Gruciani, G.; Kharazmi, A.; Liljefors, T.
来源:J Med Chem 1998,41(24),4819
合成路线图解说明:

Title compound was prepared by Claisen Schmidt condensation of 4'-cyclohexylacetophenone (I) with 3,5-dimethoxybenzaldehyde (II) in EtOH using NaOH as the catalyst.

合成路线图解说明:

Title compound was prepared by Claisen Schmidt condensation of 2'-nitroacetophenone (I) with 2,3,4-trimethoxybenzaldehyde (II) in EtOH using HCl as the catalyst.

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