PH-104-药物合成数据库

【药物名称】PH-104

化学结构式(Chemical Structure):

参考文献No.	478970
标题:	Antileishmanial chalcones: Statistical design, synthesis, and three-dimensional quantitative structure-activity relationship analysis
作者:	Nielsen, S.F.; Christensen, S.B.; Gruciani, G.; Kharazmi, A.; Liljefors, T.
来源:	J Med Chem 1998,41(24),4819

合成路线图解说明: Title compound was prepared by Claisen Schmidt condensation of 4'-cyclohexylacetophenone (I) with 3,5-dimethoxybenzaldehyde (II) in EtOH using NaOH as the catalyst.

合成路线图解说明: Title compound was prepared by Claisen Schmidt condensation of 2'-nitroacetophenone (I) with 2,3,4-trimethoxybenzaldehyde (II) in EtOH using HCl as the catalyst.