【药物名称】CGP-75254A
化学结构式(Chemical Structure):
参考文献No.35908
标题:IL-8 receptor antagonists
作者:Bryan, D.L.; Gleason, J.G.; Widdowson, K.L. (SmithKline Beecham plc)
来源:WO 9806398
合成路线图解说明:

Esterification of diacid (I) employing ethanolic HCl provided diethyl ester (II). Then, controlled partial hydrolysis with one equivalent of NaOH produced the target monoester monosodium salt.

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