【药物名称】
化学结构式(Chemical Structure):
参考文献No.476288
标题:New phthalimide derivatives with potent analgesic activity: II
作者:Antunes, R.; Batista, H.; Srivastava, R.M.; Thomas, G.; Araujo, C.C.
来源:Bioorg Med Chem Lett 1998,8(21),3071
合成路线图解说明:

Reaction of glycine (II) with phthalic anhydride (I) in a microwave oven gave phthaloylglycine (III). Subsequent condensation with phenylamidoxime (IV) in the presence of DCC in dimethoxyethane afforded the O-acyl intermediate (V), which on heating cyclized to the title oxadiazole.

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