【药物名称】AT-5015
化学结构式(Chemical Structure):
参考文献No.37128
标题:Pyrroloindole derivs. and intermediates in producing the same
作者:Shimazawa, R.; Terashima, S.; Fukuda, Y.; Oomori, Y. (Kyorin Pharmaceutical Co., Ltd.; Sagami Chemical Research Center)
来源:EP 0972775; JP 1998265473; US 6080859; WO 9832757
合成路线图解说明:

The known phenolic antibiotic (I) was treated with p-nitrophenyl chloroformate (II) in the presence of Et3N to give carbonate (III). Then, condensation of (III) with (R)-3-(hydroxymethyl)morpholine (IV) furnished the target carbamate.

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